Shaker Syndrome in Dogs
Key takeaways
Shaker syndrome describes a sudden onset of full body tremors in dogs.
- This common condition is thought to be immune mediated, but the exact cause is unknown
- Symptoms include tremors, incoordination, and head tilt
- A presumptive diagnosis is based on history, physical exam, and lack of laboratory findings on blood work and urinalysis (ie. all tests come back within normal range)
- A spinal tap or MRI can confirm diagnosis
- Treatment consists of steroids and anti-seizure/muscle relaxer medications
- Prognosis is excellent, but any dog exhibiting tremors requires prompt veterinary attention
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A closer look: Shaker Syndrome in Dogs
Shaker syndrome is a common, sudden onset, steroid responsive tremor syndrome in dogs. Vestibular signs, such as lack of balance, can also manifest with the tremors. Affected dogs manifest symptoms in early adulthood. Prognosis is excellent, but any dog exhibiting tremors or lack of balance needs to be examined by a veterinarian as soon as possible. Similar symptoms may result from conditions that require emergency care.
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Risk factors
Shaker syndrome was previously known as Little White shaker syndrome as most dogs affected were under 30lbs and white. Ongoing reporting of cases indicates any size, sex, and color of dog can be affected.
Since the exact cause of this syndrome is unknown, it is difficult to identify specific risk factors. Dogs tend to develop shaker syndrome in early adulthood.
Symptoms can worsen with activity, stress, or excitement
Shaker syndrome does not pose a significant risk to overall health, but veterinary treatment is required to reduce impact on quality of life and to rule out other, more serious, neurological conditions.
Possible causes
The condition is thought to be immune mediated, but the exact cause is unknown.
Inflammation of the part of the brain that controls balance and coordination (cerebellum) plays a role in development of symptomatic illness.
Main symptoms
Tremors may involve the entire body or be localized to a single area. Symptoms vary from very mild to severe.
Testing and diagnosis
Diagnosis of shaker syndrome is suspected based on physical exam and history. Bloodwork and urinalysis are necessary to rule out other potential causes of tremors. Cerebrospinal fluid analysis (spinal tap) or MRI can confirm the diagnosis.
Steps to Recovery
Shaker syndrome is treated with a tapering dose of immunosuppressive steroids. Diazepam, an anticonvulsant and muscle relaxant, can also be used initially if tremors are severe.
Patients with shaker syndrome respond well to medications in a few days to weeks. Treatment is continued for a month past resolution of clinical symptoms. Some dogs require steroids for life.
Prevention
Shaker syndrome cannot be prevented as the cause is unknown. The condition is not contagious.
Is Shaker Syndrome in Dogs common?
Shaker syndrome is common in dogs.
Typical Treatment
Treatment consists of:
- Steroids
- Anticonvulsants
- Muscle relaxers
